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KMID : 0378019920350020093
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New Medical Journal
1992 Volume.35 No. 2 p.93 ~ p.97
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Clinical Evaluation of Acrivastine (Semprair)^(®) on Treatment of Perennial Allergic Rhinitis
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김민식/Kim, Min-Sik
신민호/조승호/서병도/Shin, Min-Ho/Cho, Seung-Ho/Suh, Byung-Do
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Abstract
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The report is designed to evaluate the efficacy of Acrivastine (Semprair)® as an antihistamine agent in treatment of perennial allergic rhinitis. Acrivastine, a new Hi antihistamine proven effective for seasonal allergic rhinitis without significant CNS effect, was evaluated during two weeks in 30patients with perennial allergic rhinitis. All patients were divided into 4 groups (score 0, 1, 2, 3) by the symptomatic and physical evaluations.
We compared the scores on day 1, 3, 7, 14 and decided the final results of the treatment after 14 days medication. The result was that 22 patients (73.3%) while receiving, 8mg of Acrivasthine rated symptom control as excellent or good. It is concluded that 3 daily doses of 8mg of Acrivastine provide effective producing the common CNS effects of some Hl antagonists.
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KEYWORD
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